Induction of chromosomal aberrations in Allium cepa root tips cells exposed to azo dye scarlet RR.

Induction of chromosomal aberrations in Allium cepa root tips cells exposed to azo dye scarlet RR.

2015

E12017

Various chemicals were reported to be mutagenic because they are detrimental and causes inheritable changes in the genetic material. Diverse tests have been developed and employed for biomonitoring the pollutants to evaluate their toxic and mutagenic effects that are being discharged in natural environment. This study is aimed at assessing the potential of azo dye Scarlet RR to induce chromosomal and nuclear aberrations in Allium cepa test systems. A continuous exposure of root tips to the dye of different concentrations (10 micro g/L, 100 micro g/L & 1000 micro g/L) and for different time exposure (24 hr, 48 hr, 72 hr) was carried out. Cells in divisional phases were examined for mitotic index and chromosomal aberrations. Our results revealed that the dye scarlet RR produces depression in the mitotic index and various chromosomal aberrations in a dose and time dependant manner as compared to control. These results are useful in gathering the data that the dye is cytotoxic and mutagenic and may therefore lead to the damage in the genetics of the organisms.

6(4):1932-1937, RESEARCH JOURNAL OF PHARMACEUTICAL, BIOLOGICAL AND CHEMICAL SCIENCES

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