Assessment of genotoxicity of some common food preservatives using Allium cepa L. as a test plant

Assessment of genotoxicity of some common food preservatives using Allium cepa L. as a test plant

2014

E09367

Food preservatives play important role in today’s food supplies that are used to prolongthe self-life of products by protecting them from deterioration caused by micro-organisms.In this study, investigations were carried out to study the impacts of food preservativeslike butylated hydroxytoluene, butylated hydroxyanisole, sorbic acid, propyl gallate andsodium nitrate. The effects of these preservatives at concentration of 1000 ppm, 1500 ppm,2000 ppm, 2500 ppm for 4 h, 8 h and 16 h of exposure period were studied on the roottips of Allium cepa. Cytological studies revealed statistically significant (p < 0.05) inhibitionin mitotic index with an increase in concentration of the food preservatives when com-pared with the control. Most frequent cytological abnormalities observed were bridges,multipolarity, C-mitosis, stickiness and cell death. The total percentages of abnormalitieswere also increased with increasing concentration and time duration. The abnormalities(%) in root system caused by used preservatives were recorded as butylated hydroxy-toluene < butylated hydroxyanisole < sodium nitrate < sorbic acid < propyl gallate.

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