Effects of leaf extracts of Moringa oleifera on regulation of hypothyroidism and lipid profile

Effects of leaf extracts of Moringa oleifera on regulation of hypothyroidism and lipid profile

2013

E07951

The aqueous leaf extract of Moringa oleifera was evaluated for its ameliorative effect in the regulation of thyroidismin rat model. Male albino rats of 120-150 g were treated orally with doses of 500mg/kg body weight (b.w.) and250 mg/ kg b.w. of aqueous extract of Moringa oleifera leaf. Results show that T3 and T4 were increased and TSHwas decreased significantly (p>0.05) at high doses compared to those in the control group. Also, the extractsignificantly reduced (p<0.05) total cholesterol concentration and low density lipoproteins cholesterol (LDL)concentration in the serum while it had no significant effect on serum High density lipoprotein (HDL) cholesterolconcentration at all doses administered when compared with controls. The results of this study suggest that theextract may have beneficial effect on serum cholesterol concentration and a stimulant to thyroid functions.

8(2):665-669, THE BIOSCAN

Research > Published Articles