Detection of genotoxicity and chromosomal aberrations induced by Furadan and Monosodium glutamate in Allium cepa
2013
E07797
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Details
Title
Detection of genotoxicity and chromosomal aberrations induced by Furadan and Monosodium glutamate in Allium cepa
Author
Prasath, D.
Surya, S.M.
Surya, S.M.
Publication Date
2013
Call Number
E07797
Summary
The present research has been focused to investigate the genotoxic effect of a pesticide furan and a food additive monosodium glutamate. Furan is a pesticides widely used in the agricultural fields, which\n is a toxic chemical designed to kill, repel and harm living organisms. The indiscriminate use of pesticides\n has deleterious impact on human health and survival. Monosodium glutamate is a food additive which\n tends to increase nutrient value or to protect decaying nutrients during the preparations of factory made\n foods. Besides its usefulness, excessive amount of monosodium glutamate causes side effects including\n headache, dizziness, and vomiting to mankind. Genetoxicity was assessed by analyzing the chromosomal aberrations, mitotic index and the cytogenetic effects caused by food additive Monosodium glutamate and common pesticide Furadan. Allium cepa test was carried out for quick testing and detection of toxicity. Silver staining of nucleolar organizer region (AgNORs) was the preferred method for diagnosing malignant cells. The result of our study confirms that furan and monosodium glutamate induce cytotoxicity and genotoxicity in Allium cepa by causing chromosomal aberrations.
Journal Citation
3(1):11-24, SOUTH ASIAN JOURNAL OF BIOLOGICAL SCIENCES
Contact Information
harvest@worldveg.org
Record Appears in
Research > Published Articles