Extraction, characterisation and compatibility study of polysaccharides from Dillenia indica and Abelmoschus esculentus with metformin hydrochloride for development of drug delivery system
2013
E07581
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Title
Extraction, characterisation and compatibility study of polysaccharides from Dillenia indica and Abelmoschus esculentus with metformin hydrochloride for development of drug delivery system
Publication Date
2013
Call Number
E07581
Summary
The present study was carried out with an aim of studying the ability of polysaccharides extracted from Dillenia indica (DI), Abelmoschus esculentus(AE) to be used as a polymer in Drug delivery systems. Keeping in view the aim, the natural mucilaginous substances were collected from DI, AE by Acetone precipitation method and were undergone identification tests, quantitative determination of pectin by Carbazole tests and compatibility tests were carried out by FT-IR. The physicochemical tests shows the presence of pectin, quantitative determination by carbazole tests shows the presence of pectin and FT-IR report shows its compatibility with pure pectin as well as Metformin HCl (model drug). The study will provide opportunities to research to use the substance in drug delivery system.
Journal Citation
5(2):827-837, INTERNATIONAL JOURNAL OF PHARMTECH RESEARCH
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