Pyrophosphate fructose-6-phosphate phosphotransferase (PFP): an enzyme relating fructose-2,6-bisphosphate to the control of glycolysis and gluconeogenesis in plants

1985

REP.MB-2682

Pyrophosphate-D-fructose-6-phosphate phosphotransferase (PEP), an enzyme discovered in bacteria, has been accorded an important function in plants. This article traces the historical developments that lead to our current understanding of the role of PFP in gluconeogenesis (sucrose synthesis) and glycolysis taking place in the cytosol of photosynthetic and nonphotosynthetic plant tissues. Attention is given to the role of fructose-2,6-bisphosphate in controlling the activity of PFP and to the recently reported capability of PFP (a pyrophosphate-dependent enzyme) to undergo reversible conversion to phosphofructokinase (an ATP-dependent enzyme) in the presence of certain metabolites. [AS]

v.23(3):321-327, PHYSIOLOGIE VEGETALE

Research > Published Articles