Pumpkin (Cucurbita moschata) is a commercially and nutritionally important vegetable in the world. Multiple viruses such as Cucumber mosaic virus (CMV), Papaya ringspot virus (PRSV-W), Zucchini yellow mosaic virus (ZYMV), Squash leaf curl virus (SLCV), and Tomato leaf curl New Dehi virus (ToLCNDV) are serious pumpkin production constraints in the tropics. These potyviruses and geminiviruses are endemic in the pumpkin fields at the Research and Training Station of World Vegetable Center (WorldVeg), East and Southeast Asia, Kamphaeng Saen, Thailand, during November - April 2018. The susceptible check variety exhibits complete susceptibility if planted during this period in the Kamphaeng Saen fields. WorldVeg's pumpkin virus resistance breeding program screens landraces collected from various parts of the world against multiple viruses at Kamphaeng Saen during virus epidemics, followed by selection and inbreeding of virus resistant plants. We evaluated 341 pumpkin progenies of different generations (S0, S1, S2, and S3) against multiple viruses and selected 182 resistant plants within and between progeny rows. Plants were scored for other horticultural traits such as days to anthesis of the first female flower, the node at which first fruit set takes place, and fruit shape and flesh color.