Value chains are interactive systems, with the flow of products, money and information highly dependent upon relationships throughout the system. Value Chain Thinking takes a whole-of-chain perspective, emphasising the importance of market orientation and collaboration. It highlights how effective partners align their skills, resources and behaviour to deliver higher value products and services and to reduce waste, with the resultant financial returns being distributed equitably to sustain partners’ commitment. This manual helps trainers to teach Value Chain Thinking principles and decision-making processes, and provides a structure for participants to develop an Action Plan which draws together their skills in production, postharvest activities and Value Chain Thinking. It was developed and tested during “Training of Trainers” courses in Ethiopia, Malawi, Mozambique and Tanzania in 2013-2017 under the Australian Centre for International Agriculture Research (ACIAR)-funded project Improving Income and Nutrition in Eastern and Southern Africa by Enhancing Vegetable-based Farming and Food Systems in Peri-urban Corridors (VINESA).