The cotton aphid (Aphis gossypii) is one of the major pests of okra. Eleven okra varieties collected from farmers' fields in Cameroon and four aphid-resistant accessions from The World Vegetable Center (AVRDC, Asian Vegetable Research and Development Center) were evaluated from October 2012 to March 2013, and another seven aphid-resistant accessions from AVRDC were evaluated from March to July 2013 at AVRDC's Nkolbisson station, Yaounde, Cameroon. Accessions selected from these trials were screened in an advanced confirmatory screening in autumn (October-December) 2013 in Shanhua, Taiwan. Results showed that none of the farmers' landraces were resistant to aphids. Two accessions (VI041210 and VI033824) with the lowest aphid populations had the highest trichome density. Analysis of various phytochemicals in selected okra accessions revealed that higher nitrogen and potassium levels made the okra accessions susceptible to aphids during the reproductive stage of the plants. Similarly, the total phenol content was lower in moderately resistant accessions during their reproductive stage. Aphid feeding induced an increase in phenols, and to a lesser extent, tannins. Accessions VI041210 and VI033824 could be incorporated into an integrated pest management strategy to enhance productivity of okra.